מאמרים

Theses

1. M.D. Thesis: The relationship between the morphology and the cytochemistry in acute leukemias. Tel Aviv University, 1973

2. Ph.D. Thesis:  Mechanism and regulation of secretion of estradiol and placental lactogen by cultured human placental cells. Technion Israel Institute of Technology, Haifa. 1986.

 

Hypothesis-driven research

3. Hochberg Z. Treatment of familial dysautonomia with bethanecol.  J Pediatr 89;862 3, 1976.

4. Hochberg Z, Kahana L, Spiendel A, Diengott D. Plasma renin activity in  familial dysautonomia:   Unresponsiveness to a beta adrenergic blocker. Pediatrics 58;618 20, 1976. 

5. Hochberg Z. Abnormal excretion of phenolic acids in rheumatic chorea. Isr J Med Sci. 15;223 6, 1978.

6. Hochberg Z, Dickerman Z, Kaufman H, Laron Z. Evaluation of the renin aldosterone system during hypo  and hyperglycemia in children and adolescence. Hormone Res 12;16 21, 1980.

7. Hochberg Z, Hardoff D. Quantitative assessmant of nutritional rickets by urinary phosphorus excretion. Acta Paediatr Scand 70;579 80, 1981.

8. Richman RA,  Nottman DD, Hochberg Z, Moses AM. Simplifying the diagnosis of diabetes insipidus in children. Amer J Dis Child 135;839 41, 1981.

9. Hochberg Z, Richman RA. Unstable osmoreceptors and  deficient thirst in hypothalamic hypopituitarism.  Hormone Res 14;215 23, 1981.

10. Hochberg Z, Weiss J, Richman RA. Inhibin like activity in rabbit placentae. Plecenta 2;259 64, 1981.

11. Richman RA, Weiss J, Hochberg Z, Florini J. Regulation of growth hormone release: evidence against negative feedback in rat pituitary cells. Endocrinol 108;2287 92, 1981.

12. Hochberg Z, Perlman R, Benderli A, Brandes JM. The effect of glucose, 2 deoxy d glucose and insulin on estradiol secretion by cultures human trophoblast. Biochem Biophys Res Commun  108;102 9, 1982. 

13. Hochberg Z, Moses AM, Miller M, Benderly A, Richman RA. Altered osmotic threshold for vasopressin release and impaired thirst sensation: additional abnormalities in Kallman's syndrom. J Clin Endocrinol Metab 55;779 782, 1982

14. Feldman D, Chen T, Cone C, Hirst M, Shani, Benderly A, Hochberg Z. Vitamin D resistant rickets  with alopecia: cultured skin fibroblasts exhibit defective cytoplasmic receptors and unresponsiveness to 1,25(OH)2D3. J Clin Endocrinol Metab  55;1020 2, 1982.

15. Abend M,  Hochberg Z, Borochowitz Z, Berger A. Low dose continuous intravenous insulin infusion on the first day of life in a ketoacidotic newborn. Europ J Pediatr 138;345 6, 1982.

16. Hochberg Z, Benderly A. Normal osmotic threshold for vasopressin release in the hyponatremia of hypothyroidism. Hormone  Res 17;128 33, 1983.

17. Hochberg Z, Amit T, Youdim MBH, Bar Maor Y. Prolactin binding by testes of unilaterally cryptorchid rats: The effect of hCG, testosterone prolactin and orchiopexy. Acta Endocrinol   102;144 9, 1983.

18. Hochberg Z, Kutten A, Hertz P, Tatcher M, Kedar A, Benderly A. The effect of single dose radiation on cell survival and growth hormone secretion by rat anterior pituitary cells. Radiat Res 94;508 12, 1983.

19. GreiffZ, Benderly A, Levy J, Hochberg Z. Growth enhancement induced by prolonged L-dopa administration in rats. Biochem Med 30;53 8, 1983.

20. Hochberg Z, Perlman R, Brandes JM, Benderly A. Insulin regulates placental lactogen and estradiol secretion by cultured human term trophoblast. J Clin Endocrinol Metab. 57;1311-3, 1983.

21. Hochberg Z, Hertz P, Benderly A. Caffein stimulates growth hormone secretion by cultured rat pituitary cells. J Endocrinol Invest 7;59 60, 1984.

22. Hochberg Z, Bick T, Perlman R, Lahav M, Barzilai D. The modulation of placental actogen secretion by calcium: studies with cultured human term trophoblast. Moll Cell Endocrinol  37;359 62, 1984.

23. Davidai G, Kahanah  L, Hochberg  Z. Glomerulosa failure  in congenital unresponsiveness to ACTH. Clin Endocrinol 20;515 9, 1984.

24. Hochberg Z, Moses AM, Richman RA. Parathyroid hormone infusion test in children and adolescence. Mineral Electr Metab 10;113 6, 1984.

25. Kolin A. Kraiem Z, Kahana L, Hochberg Z. Effect of theophylline on urinary excretion of cyclic AMP calium and   phosphorus in newborn subjects. Mineral Electr Metab 10;359 61, 1984.

26. Zadik Z, Kahana L, Kaufman H, Benderly A, Hochberg Z. Salt loss in hypertensive form of congenital adrenal hyperplasia (11 hydroxylase deficiency). J Cln Endocrinol Metab 58;384 7,1984.

27. Chen T, Hirst MA, Cone CM, Hochberg Z, Tietze HV, Feldman D. 1,25 dihydroxyvitamin D resistance, rickets and alopecia: analysis of receptors and bioresponse in cultured fibroblasts from patients and parents. J Clin Endocrinol Metab 59;383 8, 1984.

28. Sujov P, Kellerman L, Zeltzer M, Hochberg Z. Plasma and urine osmolality in full term and preterm infants.  Acta Paediatr Scand  73;722 6, 1984.

29. Hochberg Z, Benderly A, Zadik Z. Salt loss in congenital adrenal hyperplasia due to 11 hydroxylase deficiency. Arch Dis Child 59;1092 4, 1984.

30. Hochberg Z, Levy J, Vardi P, Weisman Y, Chen T, Feldman D. 1,25 dihydroxyvitamin D resistance, rickets and alopecia.  Amer J Med 77;805 11, 1984.

31. Hochberg Z, Spiendle A, Guttman H, Colin AA. Leucine induced hypoglycemia in a family: the effect of  diphenylhydandtoin, oxprenolol and diazoxide. Hormone Res 20;218 23, 1984.

32. Sujov P, Zeltzer M, Hochberg Z. Normal plasma urine osmolality relationship in preterm infants on positive pressure   mechanical ventilation. Acta Paediatr Scand 74;601 3, 1985.

33. Abend M, Hochberg Z, Berger A, Kraiem Z. How stressful is phototherapy to newborn infants. Israel J Med Sci 21;926 7, 1985.

34. Hochberg Z, Borochowitz Z, Benderly A, Vardi P, Oren S, Spirrer Z, Heiman I Weisman Y.   Does 1,25 dihydroxyvitamin D3 participate in the regulation of hormone release from endocrine glands.  J Clin Endocrinol Metab  60;57 61, 1985.

35. Hochberg Z, Schachter Y, Benderly A, Leiberman E, Rosler A. Growth and pubertal development in congenital  adrenal hyperplasia due to 11 hydroxylase deficiency. Amer J Dis  Child 139;771 6, 1985.

36. Koren R, Ravid A, Liberman UA, Hochberg Z, Weisman Y, Novogrodski A. Defective binding and function of 1,25 dihydroxyvitamin D3 receptors in peripheral mononuclear cells of patients with end organ resistance to 1,25(OH)2D3. J Clin Invest  76;2012 5, 1985.

37. Perlman R, Barzilai D, Bick T, Hochberg Z. The effect of inhibitors on insulin regulation of hormone secretion by cultured human trophoblast.  Moll Cell Endocrinol  43;77 82, 1985.

38. Lam M, Benderly A, Ziskind G, Hochberg Z. Androgen receptor inhibition does not affect linear growth of rats. J Pediatr Endocrinol  1;217 20, 1985.

39. Hochberg Z, Bick T, Perlman R, Brandes JM, Barzilai D. The dual effect of calcium on aromatization by cultured human trophoblast. J Steroid Biochem  24;1217 9, 1986.

40. Ben Haim S, Ish Shalom S, Barzilai D, Hochberg Z.  Osmotic threshold for vasopressin release in hyperprolactinemic patients.  Mineral Electr Metab  12;210 2, 1986.

41. Hochberg  Z, Benderly A, Kahana L, Zadik Z. Requirement of mineralocorticoid in congenital adrenal hyperplasia due to   11  hydroxylase deficiency. J Clin Endocrinol Metab. 63;36 40, 1986.

42. Laufer D, Benderly A, Hochberg Z. Dental pathology in calcitriol resistant rickets.  J Oral Med 42;272 5. 1987.

43. Hochberg Z, Gardos  M, Benderly A. Psychosexual outcome of assigned females and males with 46,XX virilizing congenital adrenal hyperplasia. Europ J Pediatr 146:497 9, 1987.

44. Weisman Y, Bab I, Gazit D, Spirer Z, Jaffe M, Hochberg Z.  Long term intracaval calcium infusion therapy in end organ resistance to 1,25 dihydroxy vitamin D. Amer J Med 83;984 90, 1987.

45. Hochberg Z, Diamond E, Lischinski S, Zinder O. Prostatic ejaculate in assigned males with 46,XX congenital adrenal hyperplasia. Arch  Andrology 19;187 9, 1987.

46. Colin A, Hochberg Z, Kraiem Z. Maintenance theophylline therapy in children: Effect on urinary calcium, phosphorus and cyclic AMP excretion. Acta Paediatr Scan 76;367 8, 1987

47. Hochberg Z, Korman S. Oxandrolone therapy in boys of short stature. J Ped Endoc 2;115 20,1987

48. Hochberg Z, Perlman R, Bick T. Interrelated calcium ion  and cyclic AMP inhibition of placental lactogen secretion by cultured human term trophoblast. Acta Endocrinol 114;68 73, 1987.

49. Nagler A, Merchav S, Fabian I, Tatarsky I, Weisman Y, Hochberg Z. Myeloid progenitors from the bone marrow of patients with vitamin D resistant rickets (type II) fail to respond to 1,25(OH)2D3.  Brit J Hematol  67;267 71, 1987.

50. Merchav S, Tatarsky I, Hochberg Z. Enhancement of human granulopoiesis in vitro by biosynthetic insulin like growth factor I/somatomedin C and human growth hormone. J Clin Invest  81;791 7, 1988.

51. Hochberg Z, Bick T, Perlman R.  Two pathways of placental lactogen secretion by human trophoblast. Biochem Med Metab Biol  39;111 6, 1988.

52. Perlman R, Halabi C, Bick T, Hochberg Z.  The human placenta as a target tissue for glucagon.  Biochem Biophys Res Comm  151:1019 24, 1988.

53. Merchav S, Tatarski I, Hochberg Z.  Enhancement of erythropoiesis in vitro by human growth hormone is mediated by insulin like gowth factor I.  Br J Haematol  70;267 71, 1988.

54. Etzioni A, Pollack S, Hochberg Z. Immune function in growth hormone   deficient children treated with biosynthetic growth hormone. Acta Paediatr Scand 77:169 70, 1988.

55. Brenner B, Seligsohn U, Hochberg Z. Normal response of factor  VIII and von Willebrand factor to 1 deamino 8d arginine  vasopressin  in nephrogenic diabetes insipidus. J Clin Endocrin Metab 67;191 3, 1988.

56. Eyal A, Ish Shalom S, Hoch Z, Hochberg Z. Androgen therapy in hypogonadotropic hypogonadism: time course of erotosexual functions. Arch Androl 20;163 9, 1988.  

57. Roesler A, Weshler N, Leiberman E, Hochberg Z, , Sack J, Chemke J. 11 B Hydroxylase deficiency congenital   adrenal hyperplasia: Update of prenatal diagnosis. J Clin Endocrinol Metab 66;830 8, 1988.

58. Tirosh E, Taub Y, Scher A, Jaffe M, Hochberg Z.  Short term efficacy of thyroid hormone 

59. supplementation for patients with Down's syndrome and low borderline thyroid function.  Amer J Mental Retard 93;652 6, 1989.

60. Hochberg Z, Makhoul I.  Thyrotropin suppressibility in patients with congenital hypothyroidism. J Pediatr Endocrinol 3;251 6, 1989.

61. Barnea ER, Perlman R, Bick T, Hochberg Z.  Effects of human growth hormone upon term placental hormone secretion in vitro. Gynecol Invest  27;133 6, 1989.

62. Lewinson D, Harel Z, Shenzer P, Silbermann M, Hochberg Z. Effect of thyroid hormone and growth hormone on recovery from hypothyroidism of epiphyseal growth plate cartilage and its adjacent bone. Endocrinol 124;937 45, 1989.

63. Malloy PJ, Hochberg Z, Pike JW, Feldman D.  Abnormal binding of vitamin D receptors to deoxyribonucleic acid in a kindred with vitamin D dependent rickets, type II.   J Clin Endocrinol Metab 68;263 9, 1989.                                                  

64. Etzioni A, Hochberg Z, Pollack S, Meshulam T, Zakut V, Tzechoval E, Keisari Y, Aviram I, Spirer Z, Benderly A, Weisman Y.  Defective leucocyte fungicidal activity in end organ resistance to 1,25 dihydroxyvitamin D. Pediatr Res  25;276 9, 1989.

65. Maor G, Hochberg Z, Silbermann M.  Growth hormone stimulates the growth of mouse condylar cartilage in vitro. Acta Endocrinol 120;526 32, 1989.

66. Maor G, Hochberg Z, v d Mark K, Heinegard D, Silbermann M. Human growth hormone enhances chondrogenesis and osteogenesis in a tissue culture system of chondroprogenitor cells.  Endocrinol  125:1239 45, 1989.

67. Hertz P, Silbemann M, Even L, Hochberg Z.  The effects of sex steroids on the response of cultured rat pituicytes to growth hormone releasing hormone and somatostatin.    Endocrinol  125;581 5, 1989.

68. Bick T, Youdim MBH, Hochberg Z.  Adaptation of liver membrane somatogenic and lactogenic growth hormone (GH) binding to the spontaneous pulsation of GH secretion in the male rat. Endocrinol 125;1711 7, 1989.

69. Bick T, Youdim MBH, Hochberg Z.  The dynamics of somatogenic and lactogenic growth hormone binding:  internalization to golgi fractions in the male rat. Endocrinol 125;1718 22, 1989.

70. Ritchie HH, Hughes MR, Thompson ET, Malloy PJ, Hochberg Z, Feldman D, Pyke JW, O'Malley BW. An ochre mutation in the vitamin D receptor gene causes hereditary 1,25 dihydroxyvitamin D3 resistant rickets in three families.  Proc Natl Acad Sci (USA) 86;9783 7, 1989.

71. Barnea ER, Perlman R, Fakih H, Bick T, Kol S, Hochberg Z.  The role of catecholeamines in estradiol and progesterone secretion by cultured explants and cells of human term placentae.  Acta Endocrinol (Copenh) 121;767 72, 1989.

72. Hochberg Z, Bick T, Harel Z.  Alterations of human growth hormone binding by rat liver membranes during hypo  and hyperthyroidism. Endocrinol 126;325 9, 1990.

73. Hochberg Z, Bick T, Amit T, Barkey RJ, Youdim MBH.  Regulation of the GH receptor turnover by growth hormone. Acta Paediatr Scand [Suppl] 367;148 52, 1990.

74. Bick T, Amit T, Barkey RJ, Hertz P, Youdim MBH, Hochberg Z.  The interrelationship of growth hormone (GH), liver membrane GH receptor, serum GH binding protein activity and insulin like growth factor I (IGF I) in the male rat. Endocrinol  126:1914 20, 1990.

75. Amit T, Barkey RJ, Bick T, Hertz P, Youdim MBH, Hochberg Z. Identification of growth hormone binding protein in rat serum. Mol Cell Endocrinol 70:197 202, 1990.

76. Amit T, Barkey RJ, Youdim MBH, Hochberg Z.  A new and convenient assay of growth hormone binding protein activity in human serum.  J Clin Endocrinol Metab  71:474 9, 1990.

77. Weisman Y, Jaccard N, Legum C, Spirer Z, Yedwab G, Even L, Edelstein S, Kaye AM, Hochberg Z.  Prenatal diagnosis of vitamin D dependent rickets type II: response to 1,25 dihydroxyvitamin D in amniotic fluid cells and fetal tissues. J Clin Endocrinol Metab 71;937 43, 1990.

78. Hochberg Z.  Growth hormone and IGF I in growth plate growth.  Curr Med Liter: Growth and Growth Factors.  5;127 30, 1990.

79. Malloy PJ, Hochberg Z, Tiosano D, Hughes MR, Feldman D. The molecular basis of hereditary 1,25 dihydroxyvitamin D3 resistant rickets in seven related families. J Clin Inv 86:2071-9, 1990. 

80. Shehada N, Hazani A, Rudolf MCJ, Peleg I, Benderly A, Hochberg Z. Neurosecretory dysfunction of growth hormone secretion in thalassemia major. Acta Paediatr Scand 79;790 5, 1990.

81. Gozal D, Colin A, Jaffe M, Hochberg Z. Water, electrolyte and endocrine homeostasis in infants with bronchiolitis.  Pediatr Res 27;204 9, 1990.

82. Rudolf MCJ, Zadik Z, Linn S, Hochberg Z.  Seasonal variation in growth during growth hormone therapy. Amer J Dis Child 145;769-72, 1991.

83. Hochberg Z, Even L, Zadik Z. Mineralocorticoids in the mechanism of gynecomastia in adrenal hyperplasia caused by 11B hydroxylase deficiency. J Pediatr 118:258-60, 1991.

84. Hochberg Z, Amit T, Zadik Z. Twenty four hour profile of plasma growth hormone binding protein.  J Clin Endocrinol Metab 72:236 9, 1991.

85. Hochberg Z, Barkey RJ, Even L, Peleg I, Youdim MBH, Amit T. The effect of human growth hormone (GH) therapy on GH binding protein in GH deficient children. Acta Endocrinol (Copenh) 125;23-7, 1991.

86. Baruch Y, Amit T, Hertz P, Enat R, Youdim MBH, Hochberg Z. Decreased serum growth hormone  binding protein in patients with liver cirrhosis. J Clin Endocrinol Metab 73;777-80, 1991.

87. Amit T, Hertz P, Ish-Shalom S, Lotan R, Luboshitzki R, Youdim MBH, Hochberg Z.  Effects of hypo- or hyperthyroidism on growth hormone binding protein. Clin Endocrinol 35;159-62, 1991.

88. White PC, Dupont J, New MI, Leiberman E, Hochberg Z, Rosler A. A mutation in CYP11B1 (Arg-448 > His) associated with steroid 11ß-hydroxylase deficiency in jews of Moroccan origin. J Clin Invest 87;1664-7, 1991.

89. Hochberg Z, Amit T, Youdim MBH. The growth hormone BP as a paradigm of erythropoietin superfamily of receptors. Cell Signaling 3;85-91, 1991.

90. Amit T, Barkey RJ, Youdim MBH, Hochberg Z. Effect of human growth hormone (GH)-binding protein on GH binding to rabbit liver membranes.  Metabolism 41:732-7, 1992.

91. Altman A, Hochberg Z, Silbermann M. Interactions between growth hormone and dexamethasone in skeletal growth and bone structure of the young mouse. Calcif Tissue Int 51:298-304,1992.

92. Bick T, Hochberg Z, Amit T, Isaksson OGP, Jansson JO. Roles of pulsatility and continuity of growth hormone (GH) administration in the regulation of hepatic GH-receptors, and circulating GH-binding protein and insulin-like growth factor-I. Endocrinol 131:423-9, 1992.

93. Amit T, Barkey RJ, Youdim MBH, Hochberg Z. Modulation of human growth hormone (hGH) binding to somatogenic and lactogenic receptors by monoclonal antibodies to hGH. Cell Sign 4:553-8, 1992.

94. Hochberg Z, Hertz P, Maor G, Oiknine J, Aviram M. Growth hormone and insulin like growth factor-I increase macrophage uptake and degradation of low density lipoprotein. Endocrinol 131:430-5, 1992.

95. Amit T, Hochberg Z, Waters MJ, Barkey RJ. Growth hormone and prolactin binding proteins in mammalian serum. Endocrinol 131:1793-803, 1992.

96. Hochberg Z, Hertz P, Colin V, Ish-Shalom S, Yeshurun D, Youdim MBH, Amit T. The distal axis of growth hormone in nutritional disorders: GH-binding protein, insulin like growth factor-I (IGF-I) AND IGF-I receptors in obesity and anorexia nervosa. Metabolism 41;106-12, 1992

97. Hochberg Z, Tiosano D, Even L. Calcium therapy in calcitriol resistant rickets.  J Pediatr 121:803-8, 1992.

98. Amit T, Ish-Shalom S, Glaser B,Hochberg Z. Growth hormone binding protein in patients with acromegaly. Hormone Res 37:205-11, 1993.

99. Tirosh E, Rod R, Cohen A, Hochberg Z. Congenital adrenal hyperplasia and cerebral lateralization. Pediatr Neurol 9:198-201, 1993.

100. Hochberg Z., Leiberman E, Landau H, Koren R, Zadik Z.  Age as a determinant of the impact og growth hormone therapy on predicted adult height. Clin Endocrinol 41:331-5, 1994.

101. Hochberg Z, Amit T. The clinical significance of growth hormone binding protein.  Clin Pediat Endocrinol 2(Suppl 2):15-20, 1993.

102. Maor G, Hochberg Z, Silbermann M. Insulin like growth factor-I accelerates proliferation and differentiation of cartilage progenitor cells in cultures of neonatal mandibular condyles. Acta Endocrinol 128:56-64, 1993

103. Lewinson D, Shenzer P, Hochberg Z. Growth hormone involvement in the regulation of tartrate-resistant acid phosphatase-positive cells that are active in cartilage and bone resorption. Calcif Tissue Int 52:216-21, 1993.

104. Amit T, Hochberg Z, Barkey R. Influence of Mg2+ on detection of somatogenic and lactogenic components of GH binding protein in mammalian sera. Biochem J 293:345-9, 1993.

105. Fishman A, Hertz P, Hochberg Z Ontogenesis of the sexual dimorphism of growth hormone secretion by perifused rat hemi-pituitaries. Neuroendocrinol 57:782-788, 1993.

106. Hochberg Z,  Phillip M, Youdim MBH, Amit T. Regulation of the growth hormone (GH) receptor and GH-binding protein by GH pulsatility. Metabolism 42:1617-23, 1993.

107. Carmeli E, Hochberg Z, Livne A, Lichtentein I, Kestelboim C, Silberman M, Reznick A.  Effect of growth hormone on gastrocnemius muscle of aged rats after immobilization: biochemistry and morphology. J Appl Physiol 57:1529-35, 1993.

108. Amit T, Hartmann K, Shoshani G, Baruch Y, Youdim MBH, Hochberg Z. The turnover of growth hormone (GH) binding protein and GH-receptor in rabbit and rat. Mol Cell Endocrinol 94:149-54, 1993.

109. Baruch Y, Amit T, Hertz P, Enat R, Shoshany G, Youdim MBH, Hochberg Z. Growth hormone-binding protein and insulin-like growth factor I serum levels in partially hepatectomized rats. Hormone Res 40:173-7, 1993. 

110. Hochberg Z, Youdim MBH, Amit T. A mathematical model for appraisal of the impact of GH binding protein on GH receptor binding. Growth Regulation 4:8-13, 1994.

111. Hochberg Z, Bick T, Amit T. Stoichiometry of the pulsating growth hormone (GH) binding to the GH-binding protein and the turnover GH-receptor. Proc Soc Exp Biol Med 206:249-52, 1994.

112. Amit T, Chacham H, Dali O, Hertz P, Barkey R, Hochberg Z. The HepG2 cell line in the study of growth hormone receptor / binding protein. Mol Cell Endocrinol 101:29-36, 1994.

113. Lewinson D, Bialik G, Hochberg Z. Differential effects of hypothyroidism on the cartilage and the osteogenic process in the mandibular condyle: recovery by growth hormone and thyroxine. Endocrinol 135:1504-10, 1994.

114. Zadik Z, Chalew S, Zung A, Landau H, Leiberman E, Koren R, Voet H, Hochberg Z, Kowarski AA. Effect of long term growth hormone therapy on bone age and pubertal maturation in boys with and without classical growth hormone deficiency. J Pediatr 125:189-95, 1994.

115. Hochberg Z, Amit T, Flyvbjerg A, Dorup I. Growth hormone (GH) receptor and GH-binding protein deficiency in growth failure of potassium depleted rats. J Endocrinol 147:253-8, 1995.

116. Bick T, Amit T, Mansur M, Bar-Am O, Youdim MBH, Hochberg Z.  Regulation of cellular rabbit growth hormone (GH) receptor and GH binding protein generation in vitro. Endocrinology 137:3977-85, 1996.

117. Amit T, Bick T, Youdim MBH, Hochberg Z.  In search of the cellular site of growth hormone (GH) binding protein cleavage from the rabbit GH receptor. Endocrinology 137:3986-91, 1996.

118. Phillip M, Chalew SA, McCarter Jr RJ, Amit T, Kowarski AA, Hochberg Z. The relationship of growth rate, plasma growth hormone (GH) concentration and GH binding protein. Metabolism 45:424-429, 1996.

119. Hochberg Z, Chayen R, Reiss N, Falik Z, Makler A, Munichor M, Farkas A, Goldfarb H, Ohana N, Hiort O. Clinical biochemical and genetic findings in a large pedigree of male and female patients with 5*-reductase 2 deficiency. J Clin Endocrinol Metab 81:2821-2827, 1996.

120. Coyle B, Coffey R, Armour JAL, Gausden E, Hochberg Z, Grossman A, Britton K, Pembrey M, Reardon W, Trembath R. Pendred syndrom (goiter and sensorineural hearing loss) maps to the region containing the non-syndromic deafness gene DFNB4. Nature Gen 12:421,199

121. Even L, Weisman Y, Goldray D, Hochberg Z. Selective modulation by vitamin D of the renal response to parathyroid hormone: a study in calcitriol resistant rickets. J Clin Endocrinol Metab 81:2836-2840, 1996.

122. Gausden E, Armour JAL, Coyle B, Coffey R, Hochberg Z,  Grossman A, Reardon W, Trembath R. Thyroid peroxidase: evidence for disease gene exclusion in Pendred syndrome. Clin Endocrinol 44:441-6, 1996

123. Hochberg Z, van Lieburg A, Even, L, Brenner B, van Oost BA, Knoers NVAM. Autosomal recessive nephrogenic diabetes insipidus caused by an aquaporin-2 mutation. J Clin Endocrinol Metab 82:686-689, 1997

124. Hochberg Z, Aviram M, Rubin D, Pollack S. Decreased sensitivity to insulin like growth factor-1 in Turner syndrome astudy of monocytes and t-lymphocytes. Europ J Clin Invest 27:543-547, 1997.

125. Assy N, Hochberg Z, Amit T, Shen-Orr Z, Enat R, Baruch Y, Growth hormone - stimulated insulin like growth factor (IGF) I and IGF - binding protein-3 in liver cirrhosis. J Hepatol 27:796-802, 1997.

126. Amit T, Bergman T, Dastot F, Youdim MBH, Amselem S,  Hochberg Z.  A membrane - fixed truncated isoform of the human growth hormone receptor. J Clin Endocrinol Metab 82:3813-3817, 1997

127. Even L,  Bronstein V,  Hochberg Z. Bone maturation in girls with Turner’s syndrome. Europ J Endocrinol 138:59-62, 1998

128. Lampit M, Nave T, Hochberg Z.  Water and sodium retention during short term administration of growth hormone to short normal children. Hormone Res 50:83-88, 1998.

129. Lampit M.  Lorber A,  Vilkas DL, Nave T,  Hochberg Z. Growth hormone (GH) dependence and GH withdrawal syndrome in GH treatment of short normal children: evidence from growth and cardiac output. Eurp J Endocrinol 138:401-407, 1998

130. Assy N, Hochberg Z, Enat R, Baruch Y. Prognostic value of generation of growth hormone-stimulated insulin-like growth factor I (IGF-1) and its binding protein-3 in patients with compensated and decopensated liver cyrrhosis. Digest Dis Sci 43:1317-1321, 1998

131. Baruch Y, Assy N, Amit T, Krivoy N, Strickowski D, Shen-Orr Z, Hochberg Z. Spontaneous pulsatility and pharmacokinetics of growth hormone in liver cirrhotic patients. J Hepatol. 29:559-64, 1998.

132. Tiosano D, Gershoni R, Mandel H, Lotan R, ZahranY, Parma J, Vassart G, Pannain S, Weiss RE, Refetoff S, Hochberg Z. The hypothyroidism in an inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor. Thyroid 9:887-894, 1999.

133. Hochberg Z,  Zadik Z.  Final height in young women with Turner syndrome after growth hormone therapy: An open controlled study. Europ J Endocrinol 141:218-224, 1999

134. Amit T,   Bar-am O, Dastot F, Youdim MBH , Amselem S,  Hochberg Z.  The human growth hormone (GH) receptor and its truncated isoform:  Sulfhydryl group inactivation in the study of receptor internalization and GH-binding protein generation. Endocrinology 140:266-272, 1999.

135. Even L, Cohen A, Marbach N, Brand M, Kauli R, Sippell W, Hochberg Z. Longitudinal analysis of growth over the first three years of life in Turner syndrome. J Pediatr 137:460-464, 2000.

136. Guttmann H, Weiner Z, Nikolski E, Ish-Shalom S, Itskovitz-Eldor J, Aviram M, Reisner S, Hochberg Z. Choosing an estrogen replacement therapy in young adult women with Turner syndrome. Clin Endocrinol 54:159-164, 2001

137. Tiosano D, Weisman Y, Hochberg Z.  The role of vitamin D receptor in regulating vitamin D metabolism: a study in calcitriol-resistant rickets. J Clin Endocrinol Metab 86:1908-1912, 2001.

138. Kerem N, Guttmann H, Hochberg Z. The autosomal dominant trait of obesity, acanthosis nigricans, hypertension, ischemic heart disease and diabetes type 2. Horm Res 55:298-304, 2001

139. Zuckerman-Levine N, Tiosano D, Eisenhofer G, Bornstein, Hochberg Z. The importance of adrenocortical glucocorticoids for adrenomedullary and physiological response to stress: a study in isolated glucocorticoid deficiency. J Clin Endocrinol metab 86:5920-2924, 2001.

140. Amit T, Hochberg Z,  M. Yogev-falach M, Youdim MBH, Barkey RJ.  Shedding of growth hormone binding protein is inhibited by hydroxamic acid-based protease inhibitors: Proposed mechanism of activation of growth hormone binding proTein secretase. J Endocrinol 169:397-407, 2001. 

141. Bader T, Zoumakis E, Friedberg M, Hiroi N, Chrousos GP, Hochberg Z. Human Adipose Tissue under in Vitro Inhibition of 11-Hydroxysteroid Dehydrogenase Type 1: Differentiation and Metabolism Changes. Horm Metab Res 34:752-7, 2002

142. Lampit M, Golander A, Guttmann H, Hochberg Z. Estrogen Mini-Dose Replacement During GnRH  Agonist Therapy In Central Precocious Puberty: A Pilot Study. J Clin Endocrinol metab 87:687-690, 2002.

143. Lampit M, Hochberg Z. Prevention of growth deceleration after withdrawal of growth hormone therapy in idiopathic short stature. J Clin Endocrinol Metab 87:3573-3577, 2002

144. Snow A, Gozal E, Malhotra A, Tiosano D, Perlman R, Vega C, Shahar E, Gozal D, Hochberg Z, Pillar G. Severe hypersomnolence after pituitary/hypothalamic surgery in adolescents: clinical characteristics and potential mechanism. Pediatrics 110(6):e74, 2002

145. Tiosano D, Eisenstein I, Militianu D, Chrousos GP, Hochberg Z.11-Hydroxysteroid dehydrogenase activity in hypothalamic obesity.  J Clin Endocrinol Metab 88:379-384, 2003

146. Lampit M, Hochberg Z. Androgen therapy in constitutional delay of growth. Horm Res 59:270-275, 2003

147. Blazer S, Moreh-Waterman Y, Miller-Lotan R, Tamir A, Hochberg Z.  Suboptimal thyroxine replacement in maternal hypothyroidism may affect fetal growth and neonatal thyroid function. Obstet Gynecol 102:232-241, 2003.

148. Gelernter-Yaniv L, Feng N, Sebring NG, Hochberg Z, Yanovski JA. Associations between a polymorphism in the 11-beta hydroxysteroid dehydrogenase type 1 gene and body composition. Int J Obes Relat Metab Disord 27:983-986, 2003.

149. Zlotogorski A, Hochberg Z, Mirmirani P, Metzker A, Ben-Amitai D, Martinez Mir A, Panteleyev AA,   Christiano AM. Clinical and pathological correlations in genetically distinct forms of atrichia. Arch Dermatol 139:1591-6, 2003

150. Vottero A, Kimchi-Sarfaty C, Kratzsch J, Miller G, Lafferty A, Chrousos GP, Hochberg Z. Relative abundance of growth hormone receptor isoforms in rhesus monkey tissues and human transformed lymphocytes. Horm Metab Res 35:1-6, 2003. 

151. Vottero A, Kimchi-Sarfaty C, Kratzsch J, Chrousos GP, Hochberg Z. Transcriptional and translational regulation of the splicing isoforms of the growth hormone receptor by glucocorticoids.  Horm Metab Res 35:7-12, 2003

152. Friedberg M, Zoumakis E, Hiroi N, Bader T, Chrousos GP, Hochberg Z. Modulation of 11ß -hydroxysteroid dehydrogenase type 1 in mature human subcutaneous. J Clin Endocrinol Metab 88:385-93, 2003

153. Sherbet D, Tiosano D, Kwist KM, Hochberg Z, Auchus RJ. CYP17 mutation E305G causes isolated 17, 20-lyase deficiency by selectively altering substrate binding. J Biol Chem 278:48563-9, 2003

154. Tiulpakov A, Rubtso R, Dedov I, Peterkova V, Bezlepkina O, Chrousos GP, Hochberg Z. A novel C-terminal growth hormone receptor (GHR) mutation results in impaired GHR-Stat5 but normal Stat-3 signaling. J Clin Endocrinol Metab 90:542-7, 2005

155. Fruchter O, Kino T, Zoumakis E, Alesci S De Martino M, Chrousos GP, Hochberg Z. The human glucocorticoid receptor (GR) isoform  differentially suppresses GR-induced transactivation stimulated by synthetic slucocorticoid. J Clin Endocrinol Metab 90:3505, 2005.

156. Hochberg Z, Khaesh-Goldberg I, Partsch C-J, Zadik Zz, Bistritzer T, Cohen A, Doveh E, Sippell W, Dunkel L. Differences in infantile growth patterns in Turner syndrome girls with and without spontaneous puberty. Horm metab res 37:236-41, 2005

157. Bergman R, Schein-Goldshmid R, Hochberg Z, Ben-Izhak O, Sprecher E. The alopecia associated with vitamin D-dependent rickets type IIA and with hairless gene mutations: A comparative clinical, histological and immunohistochemical study. Arch Dermatol 141:343-351, 2005.

158. Paperna T, Gershoni-Baruch R, Badarneh K, Kasinetz L, Hochberg Z. 2005 Mutations in CYP11B1 and Congenital Adrenal Hyperplasia in Moroccan Jews.  J Clin Endocrinol Metab 90:5463-5, 2005. 

159. Sulima A, Prisinzano TE, Spande T, Whitaker N, Deschamps JR, Hochberg Z, Jacobson AE,  Rice KR. A concise method for the preparation of deuterium-labeled cortisone: synthesis of [6,7-2H]cortisone. Steroids 70: 763-769, 2005

160. Lorenz-Depiereux B, Benet-Pages A,  Eckstein G,  Tenenbaum-Rakover J, Wagenstaller J, Tiosano D, Albers N, Lichtner P, Schnabel D, Hochberg Z, Strom TM. Hereditary Hypophosphatemic Rickets with Hypercalciuria is caused by mutations in the sodium/phosphate cotransporter gene SLC34A3. Amer J Hum Gen  78:193-201,2006

161. Zuckerman–Levin N, Zinder O, Greenberg A, Jacob G,  Hochberg Z. Physiological and catecholamine response to sympathetic stimulation in Turner syndrome. Clin Endocrinol 64:410-5, 2006

162. Fruchter O, Zoumakis E, Alesci S, De Martino M, Chrousos G, Hochberg Z. Intracrine modulation of gene expression by intracellular generation of active glucocorticoids. Steroids 71:1001-6, 2006 

163. Even L, Bader T, Hochberg Z.  Nocturnal calcium, phosphorus and parathyroid pormone in the diagnosis of concealed and subclinical hypoparathyroidism in thalassemia major. Europ J Endocrinol 156:113-116, 2007

164. Ben-David S, Zuckerman-Levin N, Epelman M,   Shen-Or Z, Levin M, Sujov P, Hochberg Z   Parturition itself is the basis for fetal adrenal involution. J Clin Endocrinol Metab 92:93-7, 2007.

165. Zuckerman–Levin N, Yaniv I,  Schwartz T, Guttmann H, Hochberg Z. Normal DXA bone mineral density but frail cortical bone in Turner syndrome. Clic Endocrinol 67:, 60–64, 2007

166. Sagi L, Zuckerman-Levin N, Gawlik A, Ghizzoni L, Buyukgebiz A, Rakover Y, Bistritzer T, Admoni O, Vottero A, Baruch O, Fares F, Malecka-Tendera E, Hochberg Z. Clinical Significance of the Parental Origin of the X chromosome in Turner Syndrome. J Clin Endocrinol Metab 92:846-852, 2007

167. Tiosano D, Even L, Shen Orr Z, Hochberg Z. Recombinant hTSH in the diagnosis of congenital hypothyroidism.  J Clin Endocrinol Metab 92: 1434-1437, 2007.

168. Baroncelli GI, Bereket A, El Kholy M, Audì L, Cesur Y, Ozkan B, Rashad M, Fernández-Cancio M, Weisman Y, Saggese G, Hochberg Z. Rickets in the Middle East: role of environment and genetic predisposition. J Clin Endocrinol Metab 93:1743–1750, 2008.

169. Tiosano D, Knopf C, Koren I, Levanon N, Hartmann MF, Hochberg Z, Wudy SA. Metabolic evidence for impaired 17α-hydroxylase activity in a kindred bearing the E305G mutation for isolate 17,20-lyase activity. Eur J Endocrinol. 158:385-392, 2008. 

170. Assy N, Pruzansky Y, Gaitini D, Shen Orr Z, Hochberg Z, Baruch Y. Growth hormone-stimulated IGF-1 generation in cirrhosis reflects hepatocellular dysfunction. J Hepatol. 2008 Jul;49(1):34-42.

171. German A, Suraiya S, Tenenbaum-Rakover Y, Koren I, Pillar G, Hochberg Z. Control of Childhood congenital adrenal hyperplasia and sleep activity and quality with morning or evening glucocorticoid therapy. J Clin Endocrinol Metab. 93(12):4707-4710, 2008 

172. Hellgren G, Andersson B,  Dahlgren J, Hochberg Z, Albertsson-Wikland K A proteomic approach identified growth hormone dependent nutrition markers in children with idiopathic short stature. Proteome Sci. 2008 Dec 11;6(1):35   

174. Makhoul IR,TamirA, WeintraubZ, Rotschild A,  Bader D, Yurman S, Reich D, Bental B, Jammalieh J, Smolkin T, Sujov P, Hochberg Z. Parental and perinatal factors affecting anthropometry of very-low-birth-weight premature infants: A population-based survey. Acta Paediatr 98:963–969, 2009

175. Makhoul IR,  Tamir A, Bader D, Rotschild A, Weintraub Z, Yurman S, Reich D, Bental Y,  Jammalieh J, Smolkin T, Sujov P, Hochberg Z. In-vitro fertilisation and use of ovulation enhancers may both influence childhood height in very-low-birth-weight infants. Arch Dis Child Fetal Neonatal Ed. 94:F355-9, 2009

176. Zuckerman–Levin n, Frolova–Bishara T, Militianu D, Levin M, Aharon-Peretz J, Hochberg Z. Androgen Replacement Therapy in Turner Syndrome: A pilot study. J Clin Endocrinol Metab 94(12):4820-7, 2009 

177. Andersson B, Hellgren G, Nierop AFM, Hochberg Z, Albertsson-Wikland K. Proteins related to nutrition and fat transport were identified using a pharmaco-proteomic approach as markers for growth response to growth hormone (GH) treatment in short prebuberatal children. Proteome Science 7:40, 2009

178. Tiosano D, Navon R, Flor O, Knopf C, Hartmann MF, Wudy SA, Yakhini Z, Hochberg Z. A steroid metabolomic approach to 17α-hydroxylase/17,20 lyase deficiency. Metabolomics 6: 417-426, 2010

179. Decker R, Albertsson-Wikland K, Kriström B, Nierop AFM, Gustafsson J, Bosaeus I, Fors H, Hochberg Z, Dahlgren J. Metabolic outcome of GH treatment in prepubertal short children with and without classical GH-deficiency. Clin Endocrinol (Oxf). 73:346-54, 2010

180. Maimoun L, Philibert P, Cammas B, Audran F, Bouchard P, Fenichel P, Cartigny M, Pienkowski C, Polak M, Skordis N, Mazen I, Ocal G, Berberoglu M, Reynaud R, Baumann C, Cabrol S, Simon D, Kayemba-Kay’s K ,De Kerdanet M, Kurtz F, Leheup B, Heinrichs C, Tenoutasse S, Van Vliet G, Grüters A, Eunice M, Ammini AC, , Hochberg Z, Einaudi S, Al Mawlawi H, Jorge del Valle Nuñez C, Servant N, Lumbroso S, Paris F Sultan C. Phenotypical, biological and molecular 1 heterogeneity of 5α-reductase deficiency: an extensive international experience of 55 patients. J Clin Endocrinol Metab 96:296-307, 2011

181. Albertsson-Wikland K, Kriström B, Jonsson B, Hochberg Z. Long-Term Response to GH Therapy in Short Children With a Delayed Infancy-Childhood Transition- DICT. Pediat Res 69:504-10, 2011

182. Zuckerman-Levin N, Tsivlin L, Knopf K, Flor O, Shen-Orr Z, Levin M, Hochberg Z. 11ß–Hydroxysteroid dehydrogenase type 1 activity in short small-for-gestational-age children and in response to growth hormone therapy. Pediat Res 70(2):208-12, 2011

183. Hochberg Z, Gawlik A, Walker RS, Evolutionary fitness as a function of pubertal age in 22 subsistence-based traditional societies. Int J Pediatr Endocrinol 2011:2, 2011.

184. Gawlik A, Walker RS, Hochberg Z. Impact of infancy duration on adult size in 22 subsistence-based societies Acta Paediatr 2011 100(12):e248-52.

185. Beltrand J, Soboleva TK, Shorten PR, Hofman P, Albertsson-Wikland K, Derraik JGB, Hochberg Z, Cutfield W. Post-term Birth is Associated with Obesity in Adolescence. J Pediatr 160(5):769-73, 2012

186. Kamrath C, Hochberg Z, Remer T, Wudy S. Increased activation of the alternative 'backdoor' pathway in patients with 21-hydroxylase deficiency: evidence from urinary steroid hormone analysis. J Clin Endocrinol Metab 97:E367-75, 2011.   The Journal of Clinical Endocrinology & Metabolism best clinical research paper 2012

Editorial Auchus RJ, Miller WL, Congenital adrenal hyperplasia - more dogma bites the dust. J Clin Endocrinol Metab vol. 97 no. 3 772-775, 2012

187. Eideh H, Jonsson B, Hochberg Z. Growth of the Kalahari Desert's bushman - the Ju/'hoansi San. Acta Paediatr. 101(5):528-32, 2012

188. Meyerovitch J,  Antebi F,  Greenberg-Dotan S, Bar-Tal O, Hochberg Z. Hyperthyrotropinaemia in untreated subjects with down's syndrome aged 6 months to 64 years: a comparative analysis. Arch Dis Child. 97(7):595-8, 2012

189. Crispel Y, Katz O, Ben-Yosef  D, Hochberg Z. Effects of breastfeeding on body composition and maturational tempo in the rat. BMC-Medicine 11:114, 2013

190. Even L, Andersson B, Kriström B, Albertsson-Wikland K, Hochberg Z. The role of growth hormone in enchondroplasia and chondral osteogenesis: evaluation by X-ray of the hand. Pediatr Res 76(1):109-14, 2014.

191. Vitkin E, Ben-Dor A, Shmoish M, Hartmann MF, Yakhini Z, Wudy SA, Hochberg Z. Peer group normalization and urine to blood context in steroid metabolomics: the case of CAH and obesity. Steroids. 88(10):83-9, 2014.

192. Tiosano D, Paris F, Grimaldi M, Georgescu V, Servant N, Hochberg Z, Balaguer P, Sultan C. Evidence of ERalpha and ERbeta selectivity and partial estrogen agonism in traditional Chinese medicine. Reprod Biol Endocrinol. 10;12(1):97, 2014.

193. German A, Livshits G, Peter I, Malkin I, Dubnov J, Akons H, Shmoish M, Hochberg Z. Environmental rather than genetic factors determine the variation in the age of the infancy to childhood transition: a twins study. J Pediat 166:731-5. 2015.

194. German A, Livshits G, Peter I, Malkin I, Dubnov J, Akons H, Shmoish M, Hochberg Z. Environmental rather than genetic factors determine the variation in the age of the infancy to childhood transition: a twins study. J Pediatr. 166:731-5. 2015 

195. Tiosano D, Audi L, Climer S, Zhang W, Templeton AR, Fernández-Cancio M, Gershoni-Baruch R, Sánchez-Muro JM, El Kholy M, Hochberg Z. Latitudinal clines of the human vitamin D receptor and skin color-genes.  G3: Genes|Genomes|Genetics 6:1251-1266, 2016 

196. Blumenfeld Z, Kaidar G, Zuckerman-Levin N, Dumin E, Knopf C, Hochberg Z . Cortisol-metabolizing enzymes in polycystic ovary syndrome. Clin Med Insights Reprod Health. 10:9-13, 2016 

197. Gawlik A, Shmoish M, Hartmann MF, Malecka-Tendera E, Wudy SA, Hochberg Z. Steroid metabolomic disease signature of non-syndromic childhood obesity. J Clin Endocrinol Metab 101(11):4329-4337, 2016 

198. Anaki D, Zadikov-Mor T, Gepstein V, Hochberg Z. Face perception in women with Turner syndrome and its underlying factors. Neuropsychologia 90:274-85, 2016

199. Marakaki C, Karapanou O, Gryparis A, Hochberg Z, Chrousos G, Papadimitriou A. Early adiposity rebound and constitutional advancement of growth are associated with premature adrenarche. J Pediatr 186:72-77, 2017. 

200. Anaki D, Zadikov-Mor T, Gepstein V, Hochberg Z: Normal performance in non-visual social cognition tasks in women with Turner syndrome. Front. Endocrinol. 9:171, 2018. 

201. Marakaki C, Pervanidou P, Papassotiriou I, Mastorakos G, Hochberg Z, Chrousos G, Papadimitriou A. Greater anxiety and depression symptoms in prepubertal girls, but not in boys, with premature adrenarche. Stress 19:1-5, 2018. 

202. German A, Shmoish M, Belsky J, Hochberg Z. Outcomes of pubertal develomnet in girls as a function of pubertal onset age.  Europ J Endocrinol 2018 Oct 12;179(5):279-285 

203. Crispel y, Shaul R, Hochberg Z. The Effect of Weaning Age on the Small Intestine Mucosa of Rats. Applied Physiology, Nutrition, and Metabolism 2019 Jan 28. doi: 10.1139/apnm-2018-0454

204. Gawlik A, Shmoish M, Hartmann MF, Wudy SA, Olczak Z, Gruszczynska K, Hochberg Z. Steroid metabolomic signature of liver disease in nonsyndromic childhood obesity. Endocr Connect. 2019 May 1. pii: EC-18-0536.R2. , commentary in ESE News 

205. Gawlik AM, Shmoish M, Hartmann MF, Wudy SA, Steroid Metabolomic Signature of Insulin Resistance in Childhood Obesity  Obesity  Diabetes Care. 2019 Nov 14. dc191189, doi: 10.2337/

 

Clinical Research

   Hochberg Z. Delayed pubarche in adolescents with adrenal insufficiency. Clin Pediat 19;827 8, 1980.

   Hochberg Z. Subclinical Hashimoto's thyroiditis in gonadal dysgenesis. Isr J Med Sci 16;847 8, 1980. 

   Hochberg Z, Lahav M, Shen Or Z, Benderly A, Barzilai D. Normal values of urinary free cortisol. Isr J Med Sci 19;286 8, 1983. 

   Hochberg Z, Gilhar A, Haim S, Friedman R, Levy J, Benderly A. Calcitriol resistant rickets with alopecia. Arch Dermatol 121;646 47, 1985.

   Gershoni-Baruch R, Goldscher D, Hochberg Z. Ectrodactyly-ectodermal dysplasia-clefting syndrome and hypothalamo-pituitary insufficiency. Amer J Med Gen 68:168-172, 1997.

   Z. Hochberg, L. Even,  Amelioration of Polyuria in Nephrogenic DiabetesInsipidus due to Aquaporin-2 Deficiency.  Clin Endocrinol 49:39-44, ‏1998.

   Solt I, Gaitini D, Pery M, Hochberg Z, M. Stein, Weyl-Ben Arush M. Comparing thyroid ultrasonography to thyroid functions in long-term survivors of childhood lymphoma. Med Pediatr Oncol 35:35-40, 2000

   Leshem E, Bialik V, Hochberg Z. Ultrasonographic assessment of bone maturity in newborns. Horm Res 57:180-186, 2002

Kreher NC, Pescovitz OH, Delameter P, Tiulpakov A, Hochberg Z. Treatment of familial male-limited precocious puberty with bicalutamide and anastrozole. J Pediatr 149:416-420, 2006.

   Hochberg Z, Tamir A, Zuckerman-Levin N.  Parental Origin of the X chromosome in Turner Syndrome. J Clin Endocrinol Metab 92:eletter 13/8/2007

   Makhoul IR, Abulhija H, Smolkin T, Shehadeh N, Hochberg Z. Modified anthropometry in prepubertal Israeli children while excluding the head's weight and height. Acta Paediatr. 101(11):e496-9, 2012

   Limoni Y, Friger M, Hochberg Z. Pubertal gynecomastia coincides with the peak height velocity: does insulin growth factor 1 have a primary role? J Clin Res Pediatr Endocrinol 5(3):142-144, 2013

   Odongkara Mpora B, Piloya T, Awor S, Ngwiri T, Laigong P, Mworozi EA, Hochberg Z. Age at menarche in relation to nutritional status and critical life events among rural and urban secondary school girls in post conflict northern Uganda case studies. BMC Women's Health 14:66, DOI: 10.1186/1472-6874-14-66, 2014

   German A, Shmoish M, Hochberg Z. Predicting pubertal development by infantile and childhood height, BMI, and adiposity rebound. Pediatr Res. 2015 Oct;78(4):445-50

 

Case Reports

207. Hochberg Z. Nephrogenic diabetes insipidus in 5 siblings. Harefuah   91;691 3, 1976.

208. Hochberg Z. Hypoglycemic coma in congenital adrenal hyperplasia. Harefuah 99;322 3, 1980

209. Korman S, Borochowitz Z, Hochberg Z. Distal renal tubular acidosis with hyperkalemia due to obstructive uropathy. Harefuah 107;62 4, 1984. 

210. Vardi P, Benderly A, Etzioni A, Levi J, Hochberg Z.  Hypocalcemia induced by glucocorticoids in a child with hypoparathyroidism treated with 1 a hydroxyvitamin D3. Europ J Pediatr 144;280 2, 1985

211. Hochberg Z, Hardof D, Atias D, Spiendle A. Isolated ACTH deficiency with transitory GH deficiency. J Endocrinol Invest 8;67 70, 1985

212. Ish Shalom S, Ben Haim S, Barzilai D, Hochberg Z.  Low set osmotic threshold for vasopressin release in a patient with prolactinoma.  Hormone Res  23;78 82, 1986.

213. Davidai G, Alon U, Jaffe M, Hochberg Z. Post obstructive urinary concentrating defect: a case study in the role of prostaglandins. Acta Paediatr Scand  76;999 1002, 1987

214. Hochberg Z, Etzioni A. Genetic selection in non-classical adrenal hyperplasia. J Clin Endocrinol Metab 80:325-6, 1995.

215. Hochberg Z,  Vladowski G, Kerner H. Clinico - pathological conference: Sudden death in Turner's syndrome. Harefuah (hebrew) 129:285-8, 1995.

 

Review articles: commissioned

216. Hochberg Z. Rickets: it’s not just vitamin D deficiency. Curr Opinion Endocrinol Diabetes 8:23-28, 2001

217. Tiosano D, Hochberg Z. Endocrine complications of thalassemia. J Endocrinol Invest 24:716-723, 2001

218. Hochberg Z. Clinical physiology and pathology of the growth plate. Bailliere’s Clin Endocrinol Metab 16:399-419, 2002

219. Hochberg Z. Mechanisms of steroid impairment of growth. Horm Res 58(suppl 1):33-38, 2002

220. Hochberg Z, Bereket A, Davenport M, Delemarre - Van de Waal HA, De Schepper J, Levine MA, Shaw N, Schoenau E, Weisman Y, Zadik Z. Consensus development for the supplementation of vitamin D in childhood and adolescence. Horm Res 58:39-51, 2002

221. Hochberg Z. Extensive personal experience: vitamin D dependent rickets type 2. Horm Res 58:297-302, 2002.

222. Hochberg Z,, Pacak K, Chrousos GP. Endocrine withdrawal syndromes. Endo Rev 24:523-538, 2003

223. Hochberg Z,  Friedberg M, Yaniv L, Bader T, Tiosano D. Hypothalamic regulation of adiposity: the role of 11-hydroxysteroid dehydrogenase type 1. Horm Metab Res 36:365-9, 2004

224. Hochberg Z. Glucocorticoid withdrawal syndrome. The Endocrinologist 14:152-160, 2004

225. Hochberg Z. Requirements for vitamin D in an indoors culture. Highlights 12:19-24, 2004

226. Rudolf M,  Hochberg Z, Speiser P. Perspectives on the development of  consensus on childhood obesity. Arch Dis Child 90:994-6, 2005

227. Hochberg Z. Metabolomics of the obese. Int J Obes (Lond). 30:Suppl 2:S4. 2006

228. Fischer-Posovszky P, Wabitsch M, Hochberg Z. Endocrinology of adipose tissue – an update. Horm Metab Res  May;39:314-21, 2007

229. Hochberg Z. Juvenility in the Context of Life History Theory. Arch Dis Child 93(6):534-9, 2008

230. Mårild S, Dahlgren J, Hochberg Z. Obesity in children and adolescents – pre-treatment predictors of response to interventional life- style studies: a systematic review. Obesity Metab 5:54-59, 2009

231. Tiosano D, Hochberg Z. Hypophosphatemia: the common denominator of all rickets. J Bone Mineral Metab 27:392-401, 2009

232. Hochberg I, Hochberg Z Hypothalamic Obesity.  Endocr Dev 17:185-196, 2010 

233. Hochberg Z, Templeton A. Evolutionary perspective in skin color, vitamin D and its receptor. Hormones 9(4):307-311, 2010

234. Hochberg Z. Evolutionary perspective in child growth.  Rambam Maimonides Med J 2(3):e0057, 2011.

235. Hochberg Z. Developmental plasticity in child growth and maturation. Frontiers Pediatr Endocrinol 2(41):1-6, 2011.

236. Gawlik A, Hochberg Z. Lessons from the life history of natural fertility societies 

on child growth and maturation. Swiss Med Wkly 142: w13600, 2012. 

237.  Hochberg Z, Hochberg I, Evolutionary perspective in rickets and vitamin D. Front Endocrinol (Lausanne). 2019 May 15;10:306.

 

Review articles: authors initiative

237. Hochberg Z, Winter ST. The overweight  infant: disatvantages.  Harefuah 91;357 8, 1976

238. Hochberg Z. Neonatal thyrotoxicosis. Harefuah  94;299 300, 1978

239. Hochberg Z, Benderly A. Disorders of osmoreceptors for secretion of antidiuretic hormone.  Harefuah 102;295 7, 1982

240. Hochberg Z. Human growth hormone treatment: synthetic or extracts. (letter)  Harefuah

241. Hochberg Z.  Calcitriol resistant rickets. Harefuah 117;163 5, 1989

242. Hochberg Z, Aharonof G, Bistritzer Z, Hirsch H, Hanukoglo A. Zadik Z, Theodore R. New indication for growth hormone therapy in patients with growth failure. Harefuah 119, 243 4, 1990 

243. Hochberg Z. Growth Hormone therapy: the ethical angle. Acta Paediat Scan [Supp] 367;1 3,1990.

244. Rosenfeld R, Hochberg Z,  et al. A consensus statement on growth hormone therapy.  Acta Paediatr Scand [Suppl] 367;177 8, 1990.

245. Rudolf MCJ, Hochberg Z.  Are boys more vulnerable to psychological growth retardation?  Develop Med Child Neurol 32;1022 5, 1990.

246. Hochberg Z, Aharonof G, Bistritzer Z, Hirsch H, Hanukoglo A. Zadik Z, Theodore R. New indication for growth hormone therapy in patients with growth failure. Harefuah 119, 243 4, 1990

247. Fishman A, Hochberg Z, Growth hormone therapy for Turner's syndrome. Harefua 121:281-5, 1991.

248. Hochberg Z, Weisman Y. Calcitriol resistant rickets due to vitamin D receptor defects. Trends Endocrinol Metab 6:216-220, 1995

249. Juul A, Bernasconi S, Chatelain P, Hindmarsh P, Hochberg Z, Hokken-Koelega H, de Munick Kaizer-Scharma SMPF, Kiess W, Oberfield S, Parks J, Strasburger CJ, Volta C, Westphal O, Skakkebaek NE. Diagnosis of growth hormone (GH) deficiency and the use of GH in children with growth disorders. Hormone Res 51:284-299, 1999.

250. Amit T, Youdim MBH, Hochberg Z. Clinical Review: Does serum growth hormone (GH) binding protein reflect human GH receptor function? J Clin Endocrinol  Metab  85:927-932, 2000

251. Hochberg Z,, Pacak K, Chrousos GP. Endocrine withdrawal syndromes. Endo Rev 24: 523-38, 2003.

252. Hartman C, Hochberg Z, Shamir R. Osteoporosis in pediatrics. Isr Med Assoc J. 5:509-515, 2003 

253. Schoenau E, Saggese G, Peter F, Baroncelli GI, Shaw NJ, Crabtreed NJ, Zadik Z, Neu CM, Noordamf C, Radettig G, Hochbergh Z. From bone biology to bone analysis. Horm Res 61:257-69, 2004

254. Speiser PW, Rudolf MC, Anhalt H, Camacho-Hubner C, Chiarelli F, Eliakim A, Freemark M, Gruters A, Hershkovitz E, Iughetti L, Krude H, Latzer Y, Lustig RH, Pescovitz OH, Pinhas-Hamiel O, Rogol AD, Shalitin S, Sultan C, Stein D, Vardi P, Werther GA, Zadik Z, Zuckerman-Levin N, Hochberg Z. Consensus development: Childhood obesity. J Clin Endocrinol Metab 90:1871-1887, 2005 

255. Iughetti L, Shalitin S, de Simone M, Dahlgren J, Predieri B, Chalew S, Hochberg Z Definition and epidemiology of obesity in children and adolescent. J Endocrinol Invest 29  (Suppl 5): 34-41, 2006.

256. Hochberg Z, Albertsson-Wikland K. Evo devo of child growth. Pediatr Res 64:2-7, 2008

257. Hochberg Z. Evo-Devo of child growth II: human life history and transition between its phases. Eur J Endocrinol. 160:135-141, 2009 

258. Latzer Y, Edmunds L, Fenig S, Golan M, Gur E, Hochberg Z, Levin-Zamir D, Zubery E, Speiser PW, Stein D. Managing childhood overweight: behavior, family, pharmacology and bariatric surgery interventions. Obesity (Silver Spring). 17:411-23, 2009

259. Hochberg I, Hochberg Z. Expanding the Definition of Hypothalamic Obesity. Obes Rev. 2010 Oct;11(10):709-21

260. Hochberg Z. Evo-devo of child growth III:  Premature juvenility as an evolutionary trade-off. Horm Res Pediatr. 73:43-7, 2010

261. Latronico A-C, Hochberg Z. G protein-coupled receptors in child development, growth, and maturation. Sci. Signal. 3, re7, 2010

262. Chan L, Albertsson-Wikland K, Camacho-Hübner C, Hochberg Z. Signal transduction in child health: Closing the gap between clinical and basic research. Sci Signal 3, mr3, 2010

263. Hochberg Z., Presentation: Hormone resistance at the clinical level. Sci. Signal 3; pt1, 2010

264. Hochberg Z, Feil R, Constancia M, Fraga M, Junien C, Carel JC, Boileau P, Le Bouc Y, Deal CL, Lillycrop K, Scharfmann R, Sheppard A, Skinner M, Szyf M, Waterland RA, Waxman DJ, Whitelaw E, Ong K, Albertsson-Wikland K. Child Health, Developmental Plasticity, and Epigenetic Programming. Endocr Rev. 32:159-224, 2011

265. Martin DD, Wit JM, Hochberg Z, van Rijn RR, Fricke O, Werther G, Cameron N, Hertel T, Wudy SA, Butler G, Thodberg HH, Binder G, Ranke MB. The Use of Bone Age in Clinical Practice, Part 1. Horm Res Peadiatr76(1):1-9, 2011

266. Martin DD, Wit JM, Hochberg Z, van Rijn RR, Fricke O, Werther G, Cameron N, Hertel T, Wudy SA, Butler G, Thodberg HH, Binder G, Ranke MB. The Use of Bone Age in Clinical Practice, Part 2. Horm Res Peadiatr76(1):10-16, 2011

267. Bereket A, Kiess W, Lustig RH, Muller HL, Goldstone AP,  Yavuz Y, Hochberg Z. Hypothalamic obesity in children. Obes Rev 13:780-798, 2012

268. Zacharin M, Chanoine J-P, Cassorla F, Brink S, Hanas R, Fideleff H, Oduwole A, Shah N, Hochberg Z.  Promoting excellence in the care of pediatric endocrine diseases in the developing world. Pediatrics  131(2):e573-8, 2013

269. Hochberg Z, Belsky J. Evo-devo of human adolescence: beyond disease models of early puberty. BMC-Medicine 11:113, 2013 

   Zuckerman-Levin N, Hochberg Z, Latzer Y. Bone health in eating disorders. Obes Rev. 15(3):215-23, 2013.

270. Shaoul R, Tiosano D, Hochberg Z. Evo-Devo of Child Growth: The role of weaning in the transition from infancy to childhood. Critical Reviews in Food Science and Nutrition 25;56(6):887-95, 2016

271. Hochberg Z. On the need for national-, racial- or ethnic-specific standards for the assessment of bone maturation. Europ J Endocrinol 174:R65-70, 2016 

272. Hochberg Z. An evolutionary perspective on the obesity epidemic. Trends Endocrinol Metab 29:819-826, 2018 

273. Hochberg Z, Konner M, Emerging Adulthood, a Pre-adult Life-History Stage. Frontier Endocrinol, (accepted for publication)

 

Editorials

273. Hochberg Z. Clinical and pharmacological aspects of growth hormone therapy (Editorial). Harefuah 126:552-6, 1994

274. Hochberg Z. Growth hormone in search of a stature (editorial). Harefuah 136:39-40, 1999.

275. Hauner H, Hochberg Z. The Endocrinology of adipose tissue (Editorial). Horm Metab Res 34:605-606, 2002 

276. Brüne M, Hochberg Z. Evolutionary medicine – the quest for a better understanding of health, disease, and prevention. BMC Med 11:116, 2013

277. Brune M, Hochberg Z. Secular trends in new childhood epidemics: insights from evolutionary medicine. BMC Med 11:226, 2013

 

Books – monographs

1. ילדים - גדילה והתבגרות, מודן-תמוז, תל אביב 1988

2..  Endocrine Control of Bone Maturation. Karger, Basel, 2002

3.. Children: Growth and Puberty.  1st Books Library, 2002

4.. Evo-Devo of Child Growth. Treatise on Child Growth and Human Evolution. Wiley, New York 2012

 

 Books editor

5.  (Editor, with 10 coauthors) Practical Algorithms in Pediatric Endocrinology. Karger, Basel 1999

6.. Children: Growth and Puberty, 1st Book, Indianapolis, IN, 2002

7.Sills R (Editor).   (Series editor) Practical Algorithms in Pediatric Hematology - Oncology. Karger, Basel 2003.

8.  (Editor, with 12 coauthors)Vitamin D and Rickets. Karger, Basel 2003

9.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2004 Elsevier, Paris, 2004

10.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2005, Karger, Basel, 2005

11.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2006, Karger, Basel, 2006

12.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2007, Karger, Basel, 2007

13.  (Editor, with 12 coauthors) Practical Algorithms in Pediatric Endocrinology. 2nd edition. Karger, Basel  2007

14.Zelikovic I (Editor).   (Series editor) Practical Algorithms in Pediatric Nephrology. Karger, Basel 2008.

15.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2008, Karger, Basel, 2008

16.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2009, Karger, Basel, 2009

17.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2010, Karger, Basel, 2010

18.Carel J-C,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2011, Karger, Basel, 2011

19.Ong K,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2012, Karger, Basel, 2012

20.Ong K,  (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2013, Karger, Basel, 2013

   Shaoul R (Editor).   (Series editor) Practical Algorithms in Pediatric Gastroenterology and Nutrition. Karger, Basel, 2014.

   Ong K,  Hochberg, Z (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2014, Karger, Basel, 2014

   Ong K,  Hochberg Z. (Eds, with 12 coauthors) Yearbook of Paediatric Endocrinology 2015, Heymarker, Teddington, 2015

 

 

 

 

 

 

 

 

 

 

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